Green Rebecca, Scott L Keith, Minagar Alireza, Conrad Steven
Critical Care Medicine, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71130, USA.
Front Biosci. 2004 May 1;9:1637-41. doi: 10.2741/1250.
Sepsis associated encephalopathy (SAE) is a poorly understood condition that is associated with severe sepsis and appears to have a negative influence on survival. The incidence of encephalopathy secondary to sepsis is unknown. Amino acid derangements, blood-brain barrier disruption, abnormal neurotransmitters, and direct CNS effect are possible causes of septic encephalopathy. Research has not defined the pathogenesis of SAE.
脓毒症相关性脑病（SAE）是一种了解甚少的病症，与严重脓毒症相关，且似乎对生存率有负面影响。脓毒症继发脑病的发病率尚不清楚。氨基酸紊乱、血脑屏障破坏、神经递质异常及中枢神经系统直接效应可能是脓毒性脑病的病因。研究尚未明确SAE的发病机制。
