母猪和仔猪接种猪肺炎支原体、产毒素多杀性巴氏杆菌和胸膜肺炎放线杆菌疫苗后的抗体反应。
Antibody response in sows and piglets following vaccination against Mycoplasma hyopneumoniae, toxigenic Pasteurella multocida, and Actinobacillus pleuropneumoniae.
作者信息
Kristensen Charlotte S, Andreasen Margit, Ersbøll Annette K, Nielsen Jens P
机构信息
Department of Clinical Studies, The Royal Veterinary and Agricultural University.
出版信息
Can J Vet Res. 2004 Jan;68(1):66-70.
The aim of the experimental study was to compare the humoral immune response and occurrence of adverse effects following single or multiple simultaneous vaccination of sows against Mycoplasma hyopneumonia, toxigenic Pasteurella multocida, and Actinobacillus pleuropneumoniae. In addition, passively transferred antibodies to piglets were studied until weaning at 3 weeks of age. Fever was seen in a few sows within the first 12 hours after the 1st and 2nd vaccination. No difference in the occurrence of other adverse effects was observed between groups. Antibody levels were significantly higher in vaccinated sows and their offspring compared with the control group. This was found to be independent of single or simultaneous vaccinations with the 3 vaccines. In conclusion, applying multiple vaccines simultaneously to sows appeared not to influence the occurrence of adverse effects or the sow's serum levels of antibodies at the time of farrowing, nor the offspring's serum levels up to 3 weeks of age.
该实验研究的目的是比较母猪单次或同时多次接种猪肺炎支原体、产毒素多杀性巴氏杆菌和胸膜肺炎放线杆菌疫苗后的体液免疫反应及不良反应的发生情况。此外，还对仔猪被动转移抗体进行了研究，直至其3周龄断奶。在首次和第二次接种后的前12小时内，少数母猪出现发热。各实验组之间未观察到其他不良反应发生率的差异。与对照组相比，接种疫苗的母猪及其后代的抗体水平显著更高。研究发现这与单次接种或同时接种这三种疫苗无关。总之，同时给母猪接种多种疫苗似乎不会影响不良反应的发生、分娩时母猪的血清抗体水平，也不会影响仔猪至3周龄时的血清抗体水平。
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