一种生产具有相互连通孔隙率的羟基磷灰石物体的新方法，该方法避免了烧结。
A novel method to produce hydroxyapatite objects with interconnecting porosity that avoids sintering.
作者信息
Tadic D, Beckmann F, Schwarz K, Epple M
机构信息
Institute of Inorganic Chemistry, University of Duisburg-Essen, D-45117 Essen, Germany.
出版信息
Biomaterials. 2004 Jul;25(16):3335-40. doi: 10.1016/j.biomaterials.2003.10.007.
Porous objects of carbonated apatite were prepared by mixing polyvinyl alcohol fibres (PVA) and sodium chloride as porogens with nanocrystalline carbonated apatite powder. After cold isostatic pressing (CIP) and dissolving the porogens, the bioceramic showed an interconnecting porosity with pore diameters in the range of 250-400 microm. The method can be transposed to any material that is insoluble in water (like many polymers). Such objects are promising for bone regeneration because the interconnecting porosity in carbonated apatite provides a good environment for bone attachment and ingrowth.
通过将聚乙烯醇纤维（PVA）和作为致孔剂的氯化钠与纳米晶碳酸化磷灰石粉末混合，制备了碳酸化磷灰石多孔体。经过冷等静压（CIP）并溶解致孔剂后，这种生物陶瓷呈现出相互连通的孔隙，孔径范围为250 - 400微米。该方法可应用于任何不溶于水的材料（如许多聚合物）。这类物体在骨再生方面具有前景，因为碳酸化磷灰石中相互连通的孔隙为骨附着和向内生长提供了良好的环境。
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