Soft Matter and Molecular Biophysics Group, Department of Applied Physics, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Department of Physics and Engineering, Frostburg State University, Frostburg, MD 21532, USA.
Molecules. 2021 May 26;26(11):3190. doi: 10.3390/molecules26113190.
The development of new materials based on hydroxyapatite has undergone a great evolution in recent decades due to technological advances and development of computational techniques. The focus of this review is the various attempts to improve new hydroxyapatite-based materials. First, we comment on the most used processing routes, highlighting their advantages and disadvantages. We will now focus on other routes, less common due to their specificity and/or recent development. We also include a block dedicated to the impact of computational techniques in the development of these new systems, including: QSAR, DFT, Finite Elements of Machine Learning. In the following part we focus on the most innovative applications of these materials, ranging from medicine to new disciplines such as catalysis, environment, filtration, or energy. The review concludes with an outlook for possible new research directions.
近年来，由于技术进步和计算技术的发展，基于羟基磷灰石的新材料的发展经历了巨大的演变。本篇综述的重点是各种改进新型羟基磷灰石基材料的尝试。首先，我们评论了最常用的加工路线，突出了它们的优点和缺点。现在，我们将把重点放在其他由于其特殊性和/或最近的发展而不太常见的路线上。我们还包括一个专门介绍计算技术在这些新系统开发中的应用的版块，包括：QSAR、DFT、机器学习的有限元。在下一部分中，我们将重点介绍这些材料最具创新性的应用，从医学到催化、环境、过滤或能源等新学科。综述最后展望了可能的新研究方向。
