来自培养的微真菌顶孢霉属的丁烯内酯

Butenolides from a cultured microfungus, Acremonium sp.

作者信息

Ghisalberti Emilio L, Hargreaves Jaih R, McConville Elena

机构信息

Chemistry, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia.

出版信息

Nat Prod Res. 2004 Apr;18(2):105-9. doi: 10.1080/1478641032000101714.

DOI:10.1080/1478641032000101714

PMID:14984081

Abstract

Two related butenolides have been isolated from a culture broth of a strain of the fungus, Acremonium sp. Although the lactone acid (3) is a known compound, the structure of the lactone diacid (4), deduced by spectroscopic analysis, is assigned for the first time. This compound appears to be identical to a partly characterised metabolite isolated, along with 3, from Chaetomium indicum in 1953.

摘要

从真菌顶孢霉属（Acremonium sp.）的一个菌株的培养液中分离出了两种相关的丁烯内酯。虽然内酯酸（3）是一种已知化合物，但通过光谱分析推导得出的内酯二酸（4）的结构首次被确定。该化合物似乎与1953年从印度毛壳菌（Chaetomium indicum）中分离出的一种部分特征化的代谢产物相同，该代谢产物与化合物3一同被分离出来。