Mehta Goverdhan, Pan Subhas Chandra
Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India.
Org Lett. 2004 Mar 4;6(5):811-3. doi: 10.1021/ol0499699.
A total synthesis of the novel, biologically active epoxyquinone natural product (+/-)-jesterone has been accomplished from the readily accessible Diels-Alder adduct of cyclopentadiene and prenylated-p-benzoquinone. The approach delineated here is notable for its conceptual simplicity and efficient orchestration of a series of chemo-, regio-, and stereoselective operations. [reaction: see text]
已从环戊二烯与异戊烯基对苯醌易于获得的狄尔斯-阿尔德加成物出发，完成了新型生物活性环氧醌天然产物（±）-杰斯通酮的全合成。此处所描述的方法因其概念简单以及一系列化学、区域和立体选择性操作的高效编排而值得注意。[反应：见正文]
