Paxdaphnidines A and B, novel penta- and tetracyclic alkaloids from Daphniphyllum paxianum.
作者信息
Zhan Zha-Jun, Yang Sheng-Ping, Yue Jian-Min
机构信息
State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai, 201203, PR China.
出版信息
J Org Chem. 2004 Mar 5;69(5):1726-9. doi: 10.1021/jo035592t.
PMID:14987035
Abstract
Two novel alkaloids, paxdaphnidine A (1) with a unique pentacyclic skeleton and paxdaphnidine B (2) with an uncommon tetracyclic skeleton, were isolated from the stems and leaves of Daphniphyllum paxianum. Their structures were established by spectral methods, especially two-dimensional NMR techniques ((1)H-(1)H COSY, HSQC, HMBC, and NOESY).
摘要
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