Yang Sheng-Ping, Yue Jian-Min
State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, P. R. China.
J Org Chem. 2003 Oct 17;68(21):7961-6. doi: 10.1021/jo034804j.
Two novel major alkaloids, deoxycalyciphylline B (1) and deoxyisocalyciphylline B (2) with a unique fused hexacyclic skeleton, together with a quite recently reported alkaloid calyciphylline B (3), were isolated from the stem of Daphniphyllum subverticillatum. Their structures were established by spectral methods and chemical evidence, especially 2D NMR techniques. The structure of 1 was further confirmed by a single-crystal X-ray diffraction determination.
从轮叶虎皮楠的茎中分离出两种具有独特稠合六环骨架的新型主要生物碱，脱氧虎皮楠碱B（1）和脱氧异虎皮楠碱B（2），以及最近报道的一种生物碱虎皮楠碱B（3）。它们的结构通过光谱方法和化学证据确定，尤其是二维核磁共振技术。1的结构通过单晶X射线衍射测定进一步得到证实。
