Di Ying-Tong, He Hong-Ping, Wang Yun-Song, Li Liang-Bo, Lu Yang, Gong Jian-Bo, Fang Xin, Kong Ning-Chuan, Li Shun-Lin, Zhu Hua-Jie, Hao Xiao-Jiang
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PR China.
Org Lett. 2007 Mar 29;9(7):1355-8. doi: 10.1021/ol070218r. Epub 2007 Feb 28.
[structure: see text]. A new hexacyclic alkaloid, calydaphninone (1), containing a 4-azatricyclo[5.2.2.0(1,4)]undecan ring system, has been isolated from the leaves and twigs of Daphniphyllum calycillum (Daphniphyllaceae). Its structure was elucidated by spectral and crystallographic means. Furthermore, conformations of calydaphninone (1) in solution are discussed on the basis of NMR spectral analysis and computational (B3LYP/6-31G*) results.
[结构：见正文]。一种新的六环生物碱——水红木素（1），含有4-氮杂三环[5.2.2.0(1,4)]十一烷环系，已从水红木（虎皮楠科）的叶和嫩枝中分离得到。其结构通过光谱和晶体学方法得以阐明。此外，基于核磁共振光谱分析和计算（B3LYP/6-31G*）结果，对水红木素（1）在溶液中的构象进行了讨论。
