文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Hines G A, Watts S A, Walker C W, Voogt P A

Department of Biology, University of Alabama, Birmingham 35294.

Comp Biochem Physiol B. 1992 Jul;102(3):521-6. doi: 10.1016/0305-0491(92)90043-q.

Cell-free homogenates of male and female pyloric caeca, body wall, testis and ovary were incubated with radiolabeled 3H-androstenedione. 2. Pyloric caeca had highest rates of androstenedione conversion. The predominant metabolites in the pyloric caeca were testosterone, 5 alpha-androstane-3 beta, 17 beta-diol and 5 beta-androstane-3 beta, 17 beta-diol. 3. In body wall, testicular and ovarian homogenates, androstenedione was converted primarily to testosterone and also to 5 alpha-androstanedione and epiandrosterone. 4. Qualitative and quantitative differences in androgen metabolism in somatic and germinal tissues may be related to tissue-specific regulation of cellular metabolism.

将雄性和雌性幽门盲囊、体壁、睾丸和卵巢的无细胞匀浆与放射性标记的3H-雄烯二酮一起孵育。2. 幽门盲囊的雄烯二酮转化率最高。幽门盲囊中主要的代谢产物是睾酮、5α-雄甾烷-3β,17β-二醇和5β-雄甾烷-3β,17β-二醇。3. 在体壁、睾丸和卵巢匀浆中，雄烯二酮主要转化为睾酮，也转化为5α-雄甾二酮和表雄酮。4. 体细胞组织和生殖组织中雄激素代谢的定性和定量差异可能与细胞代谢的组织特异性调节有关。

Hines G A, Watts S A, Walker C W, Voogt P A

Department of Biology, University of Alabama, Birmingham 35294.

Comp Biochem Physiol B. 1992 Jul;102(3):521-6. doi: 10.1016/0305-0491(92)90043-q.

Cell-free homogenates of male and female pyloric caeca, body wall, testis and ovary were incubated with radiolabeled 3H-androstenedione. 2. Pyloric caeca had highest rates of androstenedione conversion. The predominant metabolites in the pyloric caeca were testosterone, 5 alpha-androstane-3 beta, 17 beta-diol and 5 beta-androstane-3 beta, 17 beta-diol. 3. In body wall, testicular and ovarian homogenates, androstenedione was converted primarily to testosterone and also to 5 alpha-androstanedione and epiandrosterone. 4. Qualitative and quantitative differences in androgen metabolism in somatic and germinal tissues may be related to tissue-specific regulation of cellular metabolism.

将雄性和雌性幽门盲囊、体壁、睾丸和卵巢的无细胞匀浆与放射性标记的3H-雄烯二酮一起孵育。2. 幽门盲囊的雄烯二酮转化率最高。幽门盲囊中主要的代谢产物是睾酮、5α-雄甾烷-3β,17β-二醇和5β-雄甾烷-3β,17β-二醇。3. 在体壁、睾丸和卵巢匀浆中，雄烯二酮主要转化为睾酮，也转化为5α-雄甾二酮和表雄酮。4. 体细胞组织和生殖组织中雄激素代谢的定性和定量差异可能与细胞代谢的组织特异性调节有关。