Reichborn-Kjennerud Ted, Bulik Cynthia M, Kendler Kenneth S, Roysamb Espen, Tambs Kristian, Torgersen Svenn, Harris Jennifer R
Division of Epidemiology, The Norwegian Institute of Public Health, Oslo, Norway.
Int J Eat Disord. 2004 Mar;35(2):123-32; discussion 133-5. doi: 10.1002/eat.10252.
To explore the extent to which genetic and environmental factors contribute to liability to placing undue importance on weight as an indicator of self-evaluation and to determine whether differences exist across genders in the nature and magnitude of these effects.
Self-report data were collected on 8,045 same-sex and opposite-sex twins, aged 18-31 years, from a population-based registry of Norwegian twins. Structural equation modeling was utilized to estimate the relative contribution of genetic and environmental factors to liability for undue influence of weight on self-evaluation, allowing for gender-specific effects.
Individual variation in undue influence of weight on self-evaluation was best explained by shared and individual environmental influences. No significant gender differences were found. Shared environmental factors accounted for 31% of the variance.
These results raise the possibility that there may be distinct sources of familial resemblance for different symptoms of bulimia nervosa as codified in the 4th ed. of the Diagnostic and Statistical Manual of Mental Disorders (American Psychiatric Association, 1994).
探讨遗传和环境因素在将体重过度视为自我评估指标方面所起作用的程度，并确定这些影响的性质和程度在性别上是否存在差异。
从挪威双胞胎人群登记处收集了8045对年龄在18至31岁之间的同性和异性双胞胎的自我报告数据。利用结构方程模型来估计遗传和环境因素对体重对自我评估产生不当影响的易感性的相对贡献，并考虑性别特异性影响。
体重对自我评估的不当影响的个体差异最好由共享环境和个体环境影响来解释。未发现显著的性别差异。共享环境因素占方差的31%。
这些结果增加了一种可能性，即如《精神疾病诊断与统计手册》第4版（美国精神病学协会，1994年）所编纂的，神经性贪食症不同症状的家族相似性可能有不同的来源。
