磁共振成像与CT对鼻咽癌的影响：放射治疗的原发肿瘤靶区勾画
Impact of magnetic resonance imaging versus CT on nasopharyngeal carcinoma: primary tumor target delineation for radiotherapy.
作者信息
Chung Na-Na, Ting Lai-Lei, Hsu Wei-Chung, Lui Louis Tak, Wang Po-Ming
机构信息
Division of Radiation Oncology, Department of Oncology, National Taiwan University, 1, Chang-Te Street, Taipei, 100, Taiwan, Republic of China.
出版信息
Head Neck. 2004 Mar;26(3):241-6. doi: 10.1002/hed.10378.
BACKGROUND
Our aim was to assess the capacity of CT versus MRI for delineating to the primary tumor extent of nasopharyngeal carcinoma (NPC) in treated patients.
METHODS
From December 1997 to April 2000, 258 patients with NPC were enrolled. We focused on the primary tumor extension and the discrepancy between CT and MRI. The delineation of tumor invasion was crucial for determination of the gross tumor volume (GTV) before radiation therapy.
RESULTS
A total of 104 patients (40.3%) had intracranial infiltration detected by MRI, whereas CT showed negative findings (p = 6.879 x 10(-11)). Once the pterygopalatine fossa was involved, the chance of intracranial invasion was increased (96.1%). The detectable percentage of pterygopalatine fossa involvement accompanying intracranial invasion was higher with MRI than with CT (96.1% vs 56.9%).
CONCLUSIONS
More detailed information about T and N classification of NPC was provided by MRI than by CT, which led to better target delineation for radiotherapy.
背景
我们的目的是评估在接受治疗的患者中，CT与MRI描绘鼻咽癌（NPC）原发肿瘤范围的能力。
方法
1997年12月至2000年4月，纳入258例NPC患者。我们重点关注原发肿瘤的扩展情况以及CT与MRI之间的差异。肿瘤浸润的描绘对于放疗前确定大体肿瘤体积（GTV）至关重要。
结果
共有104例患者（40.3%）经MRI检测出颅内浸润，而CT显示为阴性结果（p = 6.879×10⁻¹¹）。一旦翼腭窝受累，颅内侵犯的几率就会增加（96.1%）。MRI检测出颅内侵犯时翼腭窝受累的可检测百分比高于CT（96.1%对56.9%）。
结论
与CT相比，MRI提供了关于NPC的T和N分类更详细的信息，这有助于放疗时更好地勾画靶区。
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