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MR-Linac 在肿瘤放疗中的临床应用:系统评价。

Clinical application of MR-Linac in tumor radiotherapy: a systematic review.

机构信息

Department of Oncology, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.

Department of Radiation Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, 250117, China.

出版信息

Radiat Oncol. 2023 Mar 14;18(1):52. doi: 10.1186/s13014-023-02221-8.

Abstract

Recent years have seen both a fresh knowledge of cancer and impressive advancements in its treatment. However, the clinical treatment paradigm of cancer is still difficult to implement in the twenty-first century due to the rise in its prevalence. Radiotherapy (RT) is a crucial component of cancer treatment that is helpful for almost all cancer types. The accuracy of RT dosage delivery is increasing as a result of the quick development of computer and imaging technology. The use of image-guided radiation (IGRT) has improved cancer outcomes and decreased toxicity. Online adaptive radiotherapy will be made possible by magnetic resonance imaging-guided radiotherapy (MRgRT) using a magnetic resonance linear accelerator (MR-Linac), which will enhance the visibility of malignancies. This review's objectives are to examine the benefits of MR-Linac as a treatment approach from the perspective of various cancer patients' prognoses and to suggest prospective development areas for additional study.

摘要

近年来,人们对癌症有了新的认识,癌症的治疗也取得了令人瞩目的进展。然而,由于癌症发病率的上升,癌症的临床治疗模式在 21 世纪仍然难以实施。放射治疗(RT)是癌症治疗的一个重要组成部分,几乎对所有癌症类型都有帮助。随着计算机和成像技术的快速发展,RT 剂量传递的准确性不断提高。图像引导放射治疗(IGRT)的使用提高了癌症的疗效,降低了毒性。磁共振引导放射治疗(MRgRT)使用磁共振直线加速器(MR-Linac)将使在线自适应放射治疗成为可能,这将提高恶性肿瘤的可视性。本综述的目的是从各种癌症患者的预后角度探讨 MR-Linac 作为一种治疗方法的益处,并为进一步研究提出有前景的发展领域。

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