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滇黄精根的化学成分研究

[Studies on chemical constituents from the root of Polygonatum kingianum].

作者信息

Wang Yi-Fen, Mu Tian-Hui, Chen Ji-Jun, Luo Shi-De

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2003 Jun;28(6):524-7.

PMID:15015331
Abstract

OBJECTIVE

To investigate the anti-HIV constituents from the root of Polygonatum kingianum.

METHOD

The compounds were isolated by column chromatography on silica gel, Sephadex LH-20, MCI-gel CHP-20P and their structures were determined on the basis of their spectroscopic evidence including IR, MS and NMR data.

RESULT

13 compounds were isolated, of which nine compounds were identified as liquiritigenin, isoliquiritigenin, 4', 7-dihydroxy-3'-methoxyisoflavone, (6aR, 11aR)-10-hydroxy-3, 9-dimethoxypterocarpan, 5-hydroxymethyl-2-furancarboxaldehyde, salicylic acid, n-butyl-beta-D-fructopyranoside, n-butyl-beta-D-fructofuranoside, n-butyl-alpha-D-fructofuranoside.

CONCLUSION

Compounds 1-6 were obtained from this plant for the first time.

摘要

目的

研究滇黄精根中的抗HIV成分。

方法

通过硅胶柱色谱、Sephadex LH - 20、MCI - gel CHP - 20P分离化合物,并根据红外光谱(IR)、质谱(MS)和核磁共振(NMR)等光谱数据确定其结构。

结果

分离得到13个化合物,其中9个化合物被鉴定为甘草素、异甘草素、4',7 - 二羟基 - 3'- 甲氧基异黄酮、(6aR,11aR)-10 - 羟基 - 3,9 - 二甲氧基紫檀烷、5 - 羟甲基 - 2 - 呋喃甲醛、水杨酸、正丁基 - β - D - 呋喃果糖苷、正丁基 - β - D - 吡喃果糖苷、正丁基 - α - D - 呋喃果糖苷。

结论

化合物1 - 6首次从该植物中获得。

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