Blennow G, Romelsjö A, Leifman H, Leifman A, Karlsson G
Department of Social Medicine, Karolinska Institute, Sundbyberg, Sweden.
Am J Public Health. 1994 Feb;84(2):242-6. doi: 10.2105/ajph.84.2.242.
The aims of the study were (1) to estimate prevalence rates of current, regular, and long-term use of sedatives and hypnotics and the incidence of regular use in an urban population and (2) to study the association between such use of drugs and sociodemographic factors, symptoms of disease, and alcohol consumption.
Data on drug use in a random sample of 6217 adults in Stockholm County were analyzed with logistic regression.
The prevalence rate for current use of sedatives or hypnotics was 12.8% among men and 18.6% among women; the rate for regular use was 3.7% among males and 4.7% among females. The odds ratio for current use increased with age and was higher among unemployed persons and disability pensioners, high consumers of alcohol, persons with an increased level of symptoms, and widows. More than 25% of the persons who had used sedatives or hypnotics during the previous 2 weeks were regular users 6 months later. For persons aged 25 through 64 years, the annual incidence rate was 1.8% among men and 2.7% among women.
The comparatively low incidence and high prevalence of regular use implies that long-term use of sedatives and hypnotics is common.
本研究的目的是(1)估计城市人群中镇静催眠药的当前、规律和长期使用率以及规律使用的发生率，(2)研究此类药物使用与社会人口学因素、疾病症状和饮酒之间的关联。
对斯德哥尔摩县6217名成年人随机样本中的药物使用数据进行逻辑回归分析。
男性当前使用镇静催眠药的患病率为12.8%，女性为18.6%；男性规律使用的患病率为3.7%，女性为4.7%。当前使用的比值比随年龄增加，在失业者、残疾抚恤金领取者、高酒精消费者、症状水平较高者和寡妇中更高。在过去2周内使用过镇静催眠药的人中，超过25%在6个月后成为规律使用者。对于25至64岁的人群，男性的年发病率为1.8%，女性为2.7%。
规律使用的发病率相对较低但患病率较高，这意味着长期使用镇静催眠药很常见。
