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间日疟原虫血症导致白细胞直方图异常及人为自动白细胞计数——病例报告

Abnormal leukocyte histogram with a factitious automated white cell count due to Plasmodium vivax parasitemia--a case report.

作者信息

Kakkar Naveen, Guliani Sumeet

机构信息

Department of Pathology, Christian Medical College & Hospital, Ludhiana, Punjab.

出版信息

Indian J Pathol Microbiol. 2003 Oct;46(4):666-7.

PMID:15025375
Abstract

Automated hematology analyzers are designed to produce accurate and precise blood counts on specimens which are either normal or show only numerical abnormalities. However they alert the operator in samples with unusual characteristics which could result in inaccurate measurement or require review of the blood smear. Even the most sophisticated instruments cannot recognize all the significant abnormalities that can be recognized by a human observer. Spurious automated white cell counts could result from platelet aggregates, nucleated red cells, non lysis of cells and a variety of other causes. We present a case with spurious leukocytosis due to Plasmodium vivax parasitemia which was flagged by the automated analyzer.

摘要

自动血液分析仪旨在对正常或仅显示数值异常的标本进行准确且精确的血细胞计数。然而,它们会对具有异常特征的样本发出警报,这些异常特征可能导致测量不准确或需要复查血涂片。即使是最先进的仪器也无法识别所有可被人类观察者识别的重要异常情况。假性自动白细胞计数可能由血小板聚集、有核红细胞、细胞未裂解以及多种其他原因引起。我们报告一例因间日疟原虫血症导致假性白细胞增多的病例,该病例被自动分析仪标记出来。

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