Schroeder U, Kuehler A, Hennenlotter A, Haslinger B, Tronnier V M, Krause M, Pfister R, Sprengelmeyer R, Lange K W, Ceballos-Baumann A O
Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Möhlstrasse 28, D-81675 Munich, Germany.
J Neurol Neurosurg Psychiatry. 2004 Apr;75(4):648-50. doi: 10.1136/jnnp.2003.019794.
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) improves motor signs in Parkinson's disease. However, clinical studies suggest that DBS of the STN may also affect cognitive and emotional functions.
To study the impact of STN stimulation in Parkinson's disease on perception of facial expressions.
There was a selective reduction in recognition of angry faces, but not other expressions, during STN stimulation.
The findings may have important implications for social adjustment in these patients.
对丘脑底核(STN)进行深部脑刺激(DBS)可改善帕金森病的运动症状。然而,临床研究表明,对STN进行DBS也可能影响认知和情感功能。
研究帕金森病中STN刺激对面部表情感知的影响。
在STN刺激期间,愤怒面孔的识别能力出现选择性下降,而其他表情的识别能力未受影响。
这些发现可能对这些患者的社交适应具有重要意义。