Finn M M, Gosling J P, Tallon D F, Baynes S, Meehan F P, Fottrell P F
Department of Obstetrics and Gynaecology, University College, Galway, Ireland.
Gynecol Endocrinol. 1992 Jun;6(2):127-34. doi: 10.3109/09513599209046396.
A profile of salivary progesterone concentrations, based on daily samples taken over a full menstrual cycle, provides a detailed picture of changes in luteal function, at the expense of analyzing a large number of samples. Strain can be placed on analytical services by assaying daily samples instead of one or a few serum (or saliva) samples. This study sought to determine the minimum number of salivary progesterone determinations which adequately describe luteal function. Daily salivary progesterone levels from 215 cycles, of which 29 cycles had progesterone profiles indicative of luteal phase insufficiency, were analyzed to ascertain the efficiencies of various sampling patterns of reduced frequency. A single mid-luteal salivary progesterone estimation or the mid-luteal Lenton progesterone index (n = 4) satisfactorily reflected the normal luteal phase, but a frequency of one sample every 3 days over the luteal phase (n = 5-6) was necessary to allow recognition of a short luteal phase or poor progesterone surge.
基于在整个月经周期采集的每日样本得出的唾液孕酮浓度概况，能够详细呈现黄体功能的变化情况，但代价是要分析大量样本。通过检测每日样本而非一两个血清（或唾液）样本，可能会给分析服务带来压力。本研究旨在确定能够充分描述黄体功能的唾液孕酮测定的最少次数。分析了215个周期的每日唾液孕酮水平，其中29个周期的孕酮概况表明黄体期不足，以确定各种降低频率的采样模式的效率。单次黄体中期唾液孕酮测定或黄体中期Lenton孕酮指数（n = 4）能令人满意地反映正常黄体期，但在黄体期每3天采集一次样本（n = 5 - 6）的频率对于识别短黄体期或孕酮激增不足是必要的。
