Jowett Sarah L, Seal Chris J, Phillips Elizabeth, Gregory Wendy, Barton J Roger, Welfare Mark R
Northumbria Division, University of Newcastle Faculty of Medicine, North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear NE29 8NH, UK.
Clin Nutr. 2004 Apr;23(2):161-70. doi: 10.1016/S0261-5614(03)00132-8.
BACKGROUND & AIMS: Ulcerative colitis usually follows a relapsing and remitting course. Patients believe that dietary factors are important. We wished to determine the nature of and reasons for patients' dietary beliefs and their effect on relapse and nutrient intake.
In a 1-year prospective cohort study, patients' nutrient intake and disease activity were measured with a validated food frequency questionnaire and disease activity index. Food beliefs, demographics and disease characteristics were recorded. The influence of beliefs on the risk of relapse and nutrient intake were examined using chi-squared and Mann-Whitney U-tests.
One hundred and eighty-three patients were studied and 52% relapsed. Sixty-eight per cent held dietary beliefs and reported modifying their intake accordingly. The most common reported behaviour was the avoidance of milk and dairy products. Food beliefs were more common amongst those who had received dietary advice. No reported behaviour reduced the risk of relapse, but patients who avoided dairy products had a significantly lower intake of calcium. Folate intake was below UK recommended levels in 13% of patients.
Patients with ulcerative colitis believe that many foods are harmful or helpful to their disease activity. Commonly held beliefs do not modify the risk of relapse, but do adversely affect nutrient intake.
溃疡性结肠炎通常呈复发-缓解病程。患者认为饮食因素很重要。我们希望确定患者饮食观念的本质、原因及其对复发和营养摄入的影响。
在一项为期1年的前瞻性队列研究中，通过一份经过验证的食物频率问卷和疾病活动指数来测量患者的营养摄入和疾病活动情况。记录饮食观念、人口统计学特征和疾病特征。使用卡方检验和曼-惠特尼U检验来研究这些观念对复发风险和营养摄入的影响。
共研究了183例患者，其中52%复发。68%的患者持有饮食观念并据此调整了摄入量。最常报告的行为是避免食用牛奶和奶制品。饮食观念在接受过饮食建议的患者中更为常见。没有报告的行为能降低复发风险，但避免食用奶制品的患者钙摄入量显著较低。13%的患者叶酸摄入量低于英国推荐水平。
溃疡性结肠炎患者认为许多食物对其疾病活动有害或有益。普遍持有的观念不会改变复发风险，但会对营养摄入产生不利影响。
