Fowler Karen B, Stagno Sergio, Pass Robert F
Department of Pediatrics, School of Medicine, University of Alabama at Birmingham, Birmingham,USA.
Clin Infect Dis. 2004 Apr 1;38(7):1035-7. doi: 10.1086/382533. Epub 2004 Mar 15.
To examine the effect of the interval between maternal cytomegalovirus (CMV) infection and conception on the risk of congenital CMV infection, the congenital CMV infection rate was evaluated relative to the intervals between deliveries in young women. Among mothers who seroconverted between deliveries, the rate of congenital CMV infection among their offspring was highest when the delivery interval was < or =24 months. However, the risk of transmission remained elevated for women with delivery intervals of 25-48 months and for those with delivery intervals >48 months apart.
为研究孕妇巨细胞病毒（CMV）感染与受孕间隔对先天性CMV感染风险的影响，我们针对年轻女性分娩间隔，评估了先天性CMV感染率。在分娩期间血清转化的母亲中，当分娩间隔小于或等于24个月时，其后代先天性CMV感染率最高。然而，分娩间隔为25 - 48个月的女性以及分娩间隔超过48个月的女性，其传播风险仍然较高。
