Feng Wei-sheng, Zheng Xiao-ke, Wang Yan-zhi, Bi Yue-feng
Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China.
Yao Xue Xue Bao. 2003 Dec;38(12):927-30.
To study the chemical constituents from the water-extracts of pine needles of Pinus massoniana Lamb.
Chromatographic techniques were used to separate and purify compounds. Their physico-chemical properties and spectral data (UV, IR, MS, 1H-1H, 13C-1H NMR, DEPT, HMBC etc.) were used to elucidate the structures.
Three lignans were isolated from the n-BuOH fraction of water-extracts. Their structures were identified as (7S,8R)-3',4,9'-tridihydroxy-4-methoxy- 9-O-shikimoyl-7,8-dihydrobenzofuran-1'-propylneolignan (massonianoid A, I), (7S,8R)-4,9-dihydroxy-3,3'-dimethoxy-7,8- dihydrobenzofuran-1'-propylneolignan (II) and 4,4',8-trihydroxy-4,4'-dimethoxy-9-lignanolide (III).
Compound I is a new compound. While II and III were isolated from this plant for the first time.
研究马尾松松针水提取物中的化学成分。
采用色谱技术分离纯化化合物。利用其物理化学性质和光谱数据（紫外、红外、质谱、氢氢、碳氢核磁共振、无畸变极化转移增强、异核多键相关等）对结构进行解析。
从水提取物的正丁醇部位分离得到3个木脂素。其结构分别鉴定为(7S,8R)-3',4,9'-三羟基-4-甲氧基-9-O-莽草酸基-7,8-二氢苯并呋喃-1'-丙基新木脂素（马尾松新木脂素A，I）、(7S,8R)-4,9-二羟基-3,3'-二甲氧基-7,8-二氢苯并呋喃-1'-丙基新木脂素（II）和4,4',8-三羟基-4,4'-二甲氧基-9-木脂内酯（III）。
化合物I为新化合物。化合物II和III为首次从该植物中分离得到。
