Surpin Marci, Raikhel Natasha
Center for Plant Cell Biology, University of California, Riverside, California 92521, USA.
Nat Rev Mol Cell Biol. 2004 Feb;5(2):100-9. doi: 10.1038/nrm1311.
Analysis of the Arabidopsis thaliana endomembrane system has shown that plant cell viability depends on a properly functioning vacuole and intact vesicular trafficking. The endomembrane system is also essential for various aspects of plant development and signal transduction. In this review, we discuss examples of these newly discovered roles for the endomembrane system in plants, and new experimental approaches and technologies that are based on high-throughput screens, which combine chemical genetics and automated confocal microscopy.
对拟南芥内膜系统的分析表明，植物细胞的活力取决于正常运作的液泡和完整的囊泡运输。内膜系统对于植物发育和信号转导的各个方面也至关重要。在本综述中，我们讨论了内膜系统在植物中这些新发现作用的实例，以及基于高通量筛选的新实验方法和技术，这些方法和技术结合了化学遗传学和自动共聚焦显微镜。
