Vu Dinh Thiem, Hossain M Moshaddeque, Nguyen Dinh Son, Nguyen Thai Hoa, Rao Malla R, Do Gia Canh, Naficy Abdollah, Nguyen Thi Ke, Acosta Camilo J, Deen Jacqueline L, Clemens John D, Dang Duc Trach
National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
J Health Popul Nutr. 2003 Dec;21(4):304-8.
The objective of this study was to describe a mass-immunization campaign of a locally-produced oral, killed whole-cell cholera vaccine in Hue city, Vietnam. Mass immunization with a 2-dose regimen of the vaccine was conducted in 13 communes in early 1998. The total, age- and sex-specific vaccine coverage was calculated using data from the vaccination records and the government census. The number of vaccine doses procured, administered, wasted, and left over, and the human and other resources required to prepare and conduct the vaccination campaign were systematically recorded. Government expenditure for planning, procurement, and delivery of the vaccine were documented. In total, 118,555 (79%) of the 49,557 targeted population were fully vaccinated during the mass-vaccination campaign. The total expenditure for the project was US dollar 105,447, resulting in a cost per fully-vaccinated person of US dollar 0.89. Mass immunization with this locally-produced oral, killed cholera vaccine was found to be feasible and affordable with attainment of high vaccination coverage.
本研究的目的是描述在越南顺化市开展的一场针对当地生产的口服全细胞霍乱灭活疫苗的大规模免疫接种活动。1998年初，在13个公社对该疫苗进行了两剂次的大规模免疫接种。利用疫苗接种记录和政府人口普查数据计算了总体、年龄和性别特异性疫苗接种覆盖率。系统记录了采购、接种、浪费和剩余的疫苗剂量，以及筹备和开展疫苗接种活动所需的人力和其他资源。记录了政府在疫苗规划、采购和交付方面的支出。在大规模疫苗接种活动期间，目标人群中的118,555人（79%）完成了全程接种。该项目的总支出为105,447美元，每名完成全程接种者的成本为0.89美元。结果表明，使用这种当地生产的口服霍乱灭活疫苗进行大规模免疫接种是可行且经济实惠的，能够实现高接种覆盖率。
