ConSSeq：一个基于网络的应用程序，用于基于HSSP数据库并在结构背景下分析氨基酸保守性。
ConSSeq: a web-based application for analysis of amino acid conservation based on HSSP database and within context of structure.
作者信息
Higa R H, Montagner A J, Togawa R C, Kuser P R, Yamagishi M E B, Mancini A L, Pappas G, Miura R T, Horita L G, Neshich G
机构信息
Núcleo de Bioinformática, Centro Nacional de Pesquisa Agropecuária, Empresa Brasileira de Pesquisa Agropecuária, Campinas, SP, Brazil.
出版信息
Bioinformatics. 2004 Aug 12;20(12):1983-5. doi: 10.1093/bioinformatics/bth185. Epub 2004 Mar 25.
SUMMARY
A web-based application to analyze protein amino acids conservation-Consensus Sequence (ConSSeq) is presented. ConSSeq graphically represents information about amino acid conservation based on sequence alignments reported in homology-derived structures of proteins. Beyond the relative entropy for each position in the alignment, ConSSeq also presents the consensus sequence and information about the amino acids, which are predominant at each position of the alignment. ConSSeq is part of the STING Millennium Suite and is implemented as a Java Applet.
AVAILABILITY
http://sms.cbi.cnptia.embrapa.br/SMS/STINGm/consseq/, http://trantor.bioc.columbia.edu/SMS/STINGm/consseq/, http://mirrors.rcsb.org//SMS/STINGm/consseq/, http://www.es.embnet.org/SMS/STINGm/consseq/ and http://www.ar.embnet.org/SMS/STINGm/consseq/
摘要
本文介绍了一种基于网络的用于分析蛋白质氨基酸保守性的应用程序——一致性序列（ConSSeq）。ConSSeq基于蛋白质同源衍生结构中报告的序列比对，以图形方式表示有关氨基酸保守性的信息。除了比对中每个位置的相对熵外，ConSSeq还呈现了一致性序列以及关于在比对每个位置上占主导地位的氨基酸的信息。ConSSeq是STING Millennium Suite的一部分，并作为Java小程序实现。
可用性
http://sms.cbi.cnptia.embrapa.br/SMS/STINGm/consseq/，http://trantor.bioc.columbia.edu/SMS/STINGm/consseq/，http://mirrors.rcsb.org//SMS/STINGm/consseq/，http://www.es.embnet.org/SMS/STINGm/consseq/ 和 http://www.ar.embnet.org/SMS/STINGm/consseq/
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