Heitmann Berit L, Frederiksen Peder, Lissner Lauren
Research Unit for Dietary Studies and the Danish Epidemiology Science Centre, Institute of Preventive Medicine, Copenhagen, Denmark.
Obes Res. 2004 Mar;12(3):482-7. doi: 10.1038/oby.2004.54.
It has recently been demonstrated that, in middle-aged women, a wide hip circumference is a protective factor for a number of health endpoints in later years. The effect seems to be independent of both overweight and waist circumference. This paper aims to replicate this finding in another population-based sample consisting of women and men.
This was a prospective observational study consisting of a random subset of adult Danes. A total of 2987 subjects born in 1922, 1932, 1942, or 1952 and 35, 45, 55, or 65 years of age (at examination in 1987 to 1988) participated in the Danish MONICA (MONItoring trends and determinants of CArdiovascular disease) project, with measurements of height, weight, and hip and waist circumference taken. Through personal identification numbers, incidence of coronary heart disease (CHD) and cardiovascular disease (CVD) until the end of 1998 and all causes of death until 2001 were retrieved from the National Registers of Hospital Discharge. There was an average of 10 years of follow-up for incidence of CVD and CHD and 13 years of follow-up for total mortality.
Large hip circumference, relative to body size and waist circumference, predicted less incidence of CVD, CHD, and total death in women. This was not the case in men; BMI and waist circumference were the strongest independent predictors.
A large hip circumference seems to have independent and positive effects on CVD and CHD morbidity and mortality in women, but no protective effect on cardiovascular health in men. However, a borderline significant protective effect on total mortality was observed.
最近有研究表明，对于中年女性而言，较宽的臀围是其晚年多种健康指标的保护因素。这种影响似乎独立于超重和腰围。本文旨在在另一个包含男性和女性的基于人群的样本中重复这一发现。
这是一项前瞻性观察性研究，由丹麦成年人的随机子集组成。共有2987名出生于1922年、1932年、1942年或1952年且年龄为35岁、45岁、55岁或65岁（于1987年至1988年接受检查）的受试者参与了丹麦心血管疾病监测趋势和决定因素（MONICA）项目，测量了身高、体重、臀围和腰围。通过个人识别码，从国家医院出院登记处获取了截至1998年底的冠心病（CHD）和心血管疾病（CVD）发病率以及截至2001年的所有死因。对CVD和CHD发病率的随访平均为10年，对总死亡率的随访为13年。
相对于体型和腰围，较大的臀围预示着女性中CVD、CHD和全因死亡的发病率较低。男性则不然；BMI和腰围是最强的独立预测因素。
较大的臀围似乎对女性的CVD和CHD发病率及死亡率有独立的积极影响，但对男性的心血管健康没有保护作用。然而，观察到对总死亡率有临界显著的保护作用。
