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白内障类型和位置对视觉功能的影响:蓝山眼研究

Effects of cataract type and location on visual function: the Blue Mountains Eye Study.

作者信息

Chua B E, Mitchell P, Cumming R G

机构信息

Department of Public Health and Community Medicine, The University of Sydney, Australia.

出版信息

Eye (Lond). 2004 Aug;18(8):765-72. doi: 10.1038/sj.eye.6701366.

Abstract

PURPOSE

To measure the effect of cataract type, severity and location on presenting, and best-corrected visual acuity, contrast sensitivity, and glare disability.

METHODS

In all, 3654 (82.4% participation rate) eligible noninstitutionalised residents aged 49 years or older, living in two postcode areas of the Blue Mountains, Australia, received detailed eye examinations including visual acuity, contrast sensitivity, and glare disability testing. Data from right eyes were analysed using multiple regression modelling.

RESULTS

The effect of age on visual acuity and contrast sensitivity only became evident in persons aged at least 60 years. Cataract severity was inversely related to visual acuity and contrast sensitivity. Late posterior subcapsular cataract caused the greatest reduction in visual acuity. Early grade cataract caused significant reduction in contrast sensitivity at intermediate and high spatial frequencies, but late grade cataract reduced contrast sensitivity across all spatial frequencies. There was insufficient study power to detect consistent significant effect of cataract on glare disability tests or cortical cataract location on visual function.

CONCLUSIONS

Age at least 60 years, cataract type, and cataract severity were principal determinants of visual acuity and contrast sensitivity in this study. Axial and superotemporally located cortical cataract had the greatest effect on visual function tests.

摘要

目的

测量白内障类型、严重程度和位置对初始视力、最佳矫正视力、对比敏感度和眩光失能的影响。

方法

居住在澳大利亚蓝山地区两个邮政编码区域的3654名(参与率82.4%)符合条件的49岁及以上非机构化居民接受了包括视力、对比敏感度和眩光失能测试在内的详细眼部检查。使用多元回归模型分析右眼数据。

结果

年龄对视力和对比敏感度的影响仅在至少60岁的人群中明显。白内障严重程度与视力和对比敏感度呈负相关。晚期后囊下白内障导致视力下降最大。早期白内障在中高空间频率下导致对比敏感度显著降低,但晚期白内障在所有空间频率下均降低对比敏感度。研究能力不足以检测白内障对眩光失能测试或皮质性白内障位置对视觉功能的一致显著影响。

结论

在本研究中,至少60岁的年龄以及白内障类型和严重程度是视力和对比敏感度的主要决定因素。轴向和颞上皮质性白内障对视觉功能测试影响最大。

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