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嗜热栖热菌中的Embden-Meyerhof-Parnas途径和Entner-Doudoroff途径:代谢并行还是特定适应?

Embden-Meyerhof-Parnas and Entner-Doudoroff pathways in Thermoproteus tenax: metabolic parallelism or specific adaptation?

作者信息

Ahmed H, Tjaden B, Hensel R, Siebers B

机构信息

Department of Microbiology, University of Duisburg-Essen, Universitätsstrasse 5, 45117 Essen, Germany.

出版信息

Biochem Soc Trans. 2004 Apr;32(Pt 2):303-4. doi: 10.1042/bst0320303.

DOI:10.1042/bst0320303
PMID:15046594
Abstract

Genome data as well as biochemical studies have indicated that--as a peculiarity within hyperthermophilic Archaea--Thermoproteus tenax uses three different pathways for glucose metabolism, a variant of the reversible EMP (Embden-Meyerhof-Parnas) pathway and two different modifications of the ED (Entner-Doudoroff) pathway, a non-phosphorylative and a semi-phosphorylative version. An overview of the three different pathways is presented and the physiological function of the variants is discussed.

摘要

基因组数据以及生化研究表明,作为嗜热古菌中的一个特殊情况,嗜热栖热菌利用三种不同的途径进行葡萄糖代谢,一种是可逆EMP(糖酵解途径)途径的变体,以及ED(恩特纳-杜德洛夫)途径的两种不同变体,一种非磷酸化版本和一种半磷酸化版本。本文概述了这三种不同的途径,并讨论了这些变体的生理功能。

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