Goel P, Radotra A, Singh I, Aggarwal A, Dua D
Department of Obstetrics and Gynaecology, Government Medical College and Hospital, Chandigarh - 160029, India.
J Postgrad Med. 2004 Jan-Mar;50(1):12-6.
Adverse health effects of exposure to environmental tobacco smoke (ETS) among non-smokers have been studied occasionally in developing countries.
To study the effects of exposure to ETS on outcome in pregnancy
A cross-sectional study at a secondary level teaching hospital Material and Methods: Consecutive 576 non-smoking women delivering a singleton live baby were studied. A pre-designed structured questionnaire was used to record the details of exposure to ETS at home. The maternal and foetal variables were compared among those who were exposed to ETS vis-à-vis not exposed. Unpaired Student t-test was used for the comparison of continuous variables and Fisher's Exact test was used for categorical variables. Multiple logistic regression analysis was performed after including all variables found to have significant differences on univariate analysis.
Of the 576 women studied 141 (24%) were exposed to ETS. In the mothers exposed to ETS, there was a significantly higher incidence of pre-term birth (24.1% vs. 16.1%; P = 0.027) and small-for-gestation babies (31.9% vs.17.2%; p<0.001) as compared to unexposed mothers. The mean birth weight of the babies born to the mothers exposed to ETS was 138 g less than that of babies in the unexposed group (2632 -/+577 g vs. 2770 -/+562 g respectively, p = 0.014). The multiple logistic regression analyses showed that ETS exposure during pregnancy was significantly associated with a higher risk of small-for-gestation babies (OR 2.10; 95% CI: 1.27-3.48).
Exposure to ETS during pregnancy is associated with higher risk of having a small-for-gestation baby.
在发展中国家，偶尔会对非吸烟者接触环境烟草烟雾（ETS）对健康的不良影响进行研究。
研究接触ETS对妊娠结局的影响。
在一家二级教学医院进行的横断面研究。材料与方法：对连续576名分娩单胎活婴的非吸烟女性进行研究。使用预先设计的结构化问卷记录在家中接触ETS的详细情况。比较接触ETS者与未接触者的母婴变量。连续变量采用不成对学生t检验进行比较，分类变量采用Fisher精确检验。在纳入单因素分析中发现有显著差异的所有变量后，进行多因素逻辑回归分析。
在研究的576名女性中，141名（24%）接触过ETS。与未接触的母亲相比，接触ETS的母亲早产发生率显著更高（24.1%对16.1%；P = 0.027），小于胎龄儿发生率也更高（31.9%对17.2%；p<0.001）。接触ETS的母亲所生婴儿的平均出生体重比未接触组婴儿轻138克（分别为2632±577克对2770±562克，p = 0.014）。多因素逻辑回归分析表明，孕期接触ETS与小于胎龄儿风险显著增加相关（OR 2.10；95%CI：1.27 - 3.48）。
孕期接触ETS与生出小于胎龄儿的较高风险相关。
