O'Rourke Fintan, Dean Naeem, Akhtar Naveed, Shuaib Ashfaq
Stroke Prevention Clinic, University of Alberta Hospital, Mackenzie Health Sciences Centre.
CMAJ. 2004 Mar 30;170(7):1123-33. doi: 10.1503/cmaj.1031185.
Stroke is a major cause of morbidity and mortality in an aging population. The current understanding of the pathophysiology of atherosclerotic diseases, the most common cause of stroke, and the evidence for existing therapeutic interventions for the prevention of stroke are presented. Specifically, we review the evidence for antiplatelet agents, anticoagulants, antihypertensive medications, lipid-lowering agents and carotid endarterectomy for stroke prevention.
中风是老年人群发病和死亡的主要原因。本文介绍了对动脉粥样硬化性疾病（中风最常见的病因）病理生理学的当前认识以及现有预防中风治疗干预措施的证据。具体而言，我们综述了抗血小板药物、抗凝剂、抗高血压药物、降脂药物和颈动脉内膜切除术预防中风的证据。
