迟发型急性麻疹脑炎：神经影像学和免疫学发现

Acute measles encephalitis of the delayed type: neuroradiological and immunological findings.

作者信息

Barthez Carpentier M A, Billard C, Maheut J, Jourdan M L, Degenne D, Ruchoux M M, Goudeau A, Santini J J

机构信息

Unité de Neurologie-Neurochirurgie Infantile, Hôpital Clocheville, Tours, France.

出版信息

Eur Neurol. 1992;32(4):235-7. doi: 10.1159/000116831.

DOI:10.1159/000116831

PMID:1505595

Abstract

A case of delayed acute measles encephalitis in an immunosuppressed child is reported. Detailed immunological studies have shown defective humoral immunity (defective IgA, IgG2 and IgG3) and decreased natural killer activity. Neuroradiological examination by magnetic resonance imaging revealed several high signal lesions on T2-weighted images in the gray matter without clinical or pathological correlation. The implications of these findings are discussed.

摘要

报告了一例免疫抑制儿童迟发性急性麻疹脑炎病例。详细的免疫学研究显示体液免疫缺陷（IgA、IgG2和IgG3缺陷）以及自然杀伤活性降低。通过磁共振成像进行的神经放射学检查显示，在灰质的T2加权图像上有几个高信号病变，与临床或病理无关。讨论了这些发现的意义。