Chadwick D W, Martin S, Buxton P H, Tomlinson A H
J Neurol Neurosurg Psychiatry. 1982 Aug;45(8):680-4. doi: 10.1136/jnnp.45.8.680.
A 20-year-old girl developed a subacute neurological illness characterized by seizures and epilepsia partialis continua, which resulted in her death within 10 weeks of her first symptom. Although she had a history of unusual reactions to viral infections, there was no evidence of any underlying disorder resulting in immunosuppression. Histopathology demonstrated the presence of dense infection with measles virus. The unusual clinical features of this cases suggest that measles virus may be responsible for a wide spectrum of neurological disease ranging from measles inclusion body encephalitis on the one hand to subacute sclerosing panencephalitis on the other.
一名20岁女孩患上了一种亚急性神经系统疾病,其特征为癫痫发作和持续性部分性癫痫,首次出现症状后10周内死亡。尽管她有病毒感染后出现异常反应的病史,但没有证据表明存在导致免疫抑制的任何潜在疾病。组织病理学显示存在麻疹病毒的密集感染。该病例不寻常的临床特征表明,麻疹病毒可能是导致从麻疹包涵体脑炎到亚急性硬化性全脑炎等一系列广泛神经系统疾病的原因。