Peet Malcolm
Swallownest Court Hospital, Aughton Road, Sheffield S26 4TH, UK.
Br J Psychiatry Suppl. 2004 Apr;47:S102-5. doi: 10.1192/bjp.184.47.s102.
Diabetes is more common in people with schizophrenia than in the general population.
To explore the possible reasons for the association between diabetes and schizophrenia.
Diet and other lifestyle factors in patients with schizophrenia were reviewed as risk factors for diabetes.
People with schizophrenia show features of the metabolic syndrome at the onset of illness, before treatment. They also eat a poor diet, take little exercise and have high rates of smoking. Food intake may be increased further by antipsychotic medication. Nutritional factors appear to have a key role in the development of diabetes in patients with schizophrenia and may also affect the outcome and severity of schizophrenia. A common pathway through which diet might contribute to the development of both diabetes and schizophrenia is proposed.
Lifestyle factors may influence outcomes in both diabetes and schizophrenia. Lifestyle interventions are the key to improving the long-term health of people with schizophrenia.
糖尿病在精神分裂症患者中比在普通人群中更为常见。
探讨糖尿病与精神分裂症之间关联的可能原因。
回顾精神分裂症患者的饮食及其他生活方式因素作为糖尿病的风险因素。
精神分裂症患者在疾病发作时、治疗前就表现出代谢综合征的特征。他们饮食不佳、运动少且吸烟率高。抗精神病药物可能会进一步增加食物摄入量。营养因素似乎在精神分裂症患者糖尿病的发生中起关键作用，也可能影响精神分裂症的结局和严重程度。提出了饮食可能导致糖尿病和精神分裂症发生的共同途径。
生活方式因素可能影响糖尿病和精神分裂症的结局。生活方式干预是改善精神分裂症患者长期健康的关键。
