来自喜马拉雅大黄的蒽酮碳苷。

Anthrone C-glucosides from Rheum emodi.

作者信息

Krenn Liselotte, Pradhan Riddhi, Presser Armin, Reznicek Gottfried, Kopp Brigitte

机构信息

Institute of Pharmacognosy, University of Vienna, Austira.

出版信息

Chem Pharm Bull (Tokyo). 2004 Apr;52(4):391-3. doi: 10.1248/cpb.52.391.

DOI:10.1248/cpb.52.391

PMID:15056949

Abstract

In a study of the anthraderivatives in roots of Rheum emodi, three new anthrone C-glucosides, named 10-hydroxycascaroside C (1), 10-hydroxycascaroside D (2) and 10R-chrysaloin 1-O-beta-D-glucopyranoside (3) were isolated besides the rare compounds cascaroside C (4), cascaroside D (5) and cassialoin (6). Additionally the investigation resulted in the isolation of an acetylated chrysophanol glucoside, 8-O-beta-D-(6'-O-acetyl)glucopyranosyl-chrysophanol (7). The structures were established by comprehensive spectroscopic investigations.

摘要

在一项对喜马拉雅大黄根中蒽衍生物的研究中，除了稀有化合物大黄苷C（4）、大黄苷D（5）和芦荟大黄素苷（6）外，还分离出了三种新的蒽酮碳苷，分别命名为10-羟基大黄苷C（1）、10-羟基大黄苷D（2）和10R-大黄素甲醚1-O-β-D-吡喃葡萄糖苷（3）。此外，该研究还分离出了一种乙酰化的大黄酚葡萄糖苷，8-O-β-D-（6'-O-乙酰基）吡喃葡萄糖基-大黄酚（7）。通过全面的光谱研究确定了其结构。