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Protein kinase CK2: a new view of an old molecular complex.
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The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta.
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Highlighting protein kinase CK2 movement in living cells.
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Mass Spectrometry Reveals Protein Kinase CK2 High-Order Oligomerization via the Circular and Linear Assembly.
ACS Chem Biol. 2016 Jun 17;11(6):1511-7. doi: 10.1021/acschembio.6b00064. Epub 2016 Mar 29.
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Protein kinase CK2 in human diseases.
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Identifying interaction motifs in CK2beta--a ubiquitous kinase regulatory subunit.
Trends Biochem Sci. 2006 Dec;31(12):654-61. doi: 10.1016/j.tibs.2006.10.005. Epub 2006 Nov 3.
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Autophosphorylation at the regulatory beta subunit reflects the supramolecular organization of protein kinase CK2.
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Discrimination between the activity of protein kinase CK2 holoenzyme and its catalytic subunits.
FEBS Lett. 2006 Jul 10;580(16):3948-52. doi: 10.1016/j.febslet.2006.06.031. Epub 2006 Jun 21.
9
The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin.
J Mol Biol. 2008 Mar 14;377(1):1-8. doi: 10.1016/j.jmb.2008.01.008. Epub 2008 Jan 11.
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The role of the N-terminal domain in the regulation of the "constitutively active" conformation of protein kinase CK2α: insight from a molecular dynamics investigation.
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Structure-Activity Relationship Studies of Tetracyclic Pyrrolocarbazoles Inhibiting Heterotetrameric Protein Kinase CK2.
Molecules. 2024 Dec 27;30(1):63. doi: 10.3390/molecules30010063.
2
In Skeletal Muscle Fibers, Protein Kinase Subunit CSNK2A1/CK2α Is Required for Proper Muscle Homeostasis and Structure and Function of Neuromuscular Junctions.
Cells. 2022 Dec 7;11(24):3962. doi: 10.3390/cells11243962.
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The Role of Protein Kinase CK2 in Development and Disease Progression: A Critical Review.
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Phosphorylation of plant virus proteins: Analysis methods and biological functions.
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Casein kinase 2 attenuates brain injury induced by intracerebral hemorrhage via regulation of NR2B phosphorylation.
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CK2β Is a Gatekeeper of Focal Adhesions Regulating Cell Spreading.
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Evaluation of a Selective Chemical Probe Validates That CK2 Mediates Neuroinflammation in a Human Induced Pluripotent Stem Cell-Derived Microglial Model.
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Synthesis and SAR of Tetracyclic Inhibitors of Protein Kinase CK2 Derived from Furocarbazole W16.
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CASEIN KINASE2-Dependent Phosphorylation of PHOSPHATE2 Fine-tunes Phosphate Homeostasis in Rice.
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Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors.
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Cell biology: join the crowd.
Nature. 2003 Sep 4;425(6953):27-8. doi: 10.1038/425027a.
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Modulation of human checkpoint kinase Chk1 by the regulatory beta-subunit of protein kinase CK2.
Oncogene. 2003 Aug 7;22(32):4933-42. doi: 10.1038/sj.onc.1206721.
3
Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.
J Mol Biol. 2003 Jul 25;330(5):925-34. doi: 10.1016/s0022-2836(03)00638-7.
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Diversity of protein-protein interactions.
EMBO J. 2003 Jul 15;22(14):3486-92. doi: 10.1093/emboj/cdg359.
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A new role for an old kinase: CK2 and the circadian clock.
Nat Neurosci. 2003 Mar;6(3):208-10. doi: 10.1038/nn0303-208.
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A role for CK2 in the Drosophila circadian oscillator.
Nat Neurosci. 2003 Mar;6(3):251-7. doi: 10.1038/nn1007.
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Live-cell fluorescence imaging reveals the dynamics of protein kinase CK2 individual subunits.
Mol Cell Biol. 2003 Feb;23(3):975-87. doi: 10.1128/MCB.23.3.975-987.2003.
8
Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality.
Mol Cell Biol. 2003 Feb;23(3):908-15. doi: 10.1128/MCB.23.3.908-915.2003.
9
Dynamic localization/association of protein kinase CK2 subunits in living cells: a role in its cellular regulation?
Ann N Y Acad Sci. 2002 Nov;973:272-7. doi: 10.1111/j.1749-6632.2002.tb04648.x.
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A kinetic framework for a mammalian RNA polymerase in vivo.
Science. 2002 Nov 22;298(5598):1623-6. doi: 10.1126/science.1076164.
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