Clarkin John F, Levy Kenneth N, Lenzenweger Mark F, Kernberg Otto F
Personality Disorders Institute and Department of Psychiatry, Weill Medical College of Cornell University, Westchester Division, White Plains, NY 10605, USA.
J Pers Disord. 2004 Feb;18(1):52-72. doi: 10.1521/pedi.18.1.52.32769.
The Personality Disorder Institute/Borderline Personality Disorder Research Foundation randomized control trial (PDI/BPDRF RCT) is a controlled outcome study for borderline personality disorder (BPD), in which 90 participants were randomized to one of three manualized and monitored, active psychosocial treatment conditions. These treatments are: (a) Transference-Focused Psychotherapy (TFP; Clarkin, Yeomans, & Kernberg, 1999), a treatment for BPD based on object-relational and psychoanalytic principles first applied to BPD by Kernberg (1996), notable for its particular emphasis on interpretation of object relations activated in the ongoing therapeutic relationship; (b) Dialectical Behavior Therapy (DBT; Linehan, 1993), a popular treatment for BPD, with evidence of efficacy (Linehan, Armstrong, Suarez, Allmon, & Heard, 1991) that emphasizes a balance between acceptance and change in its combination of cognitive-behavioral and Zen principles; and (c) supportive psychotherapy (Rockland, 1992), another object-relational and psychoanalytically based treatment for BPD which, in contrast to TFP, eschews transference interpretation and places primary emphasis on development of a collaborative engagement with the patient to foster identity development. Patients received medication, if clearly indicated, according to the treatment algorithm developed by Soloff (2000). This article describes the significance and rationale of the study and the overall design, methods, plan of analysis, and demographic characteristics of the recruited sample of patients.
人格障碍研究所/边缘型人格障碍研究基金会随机对照试验（PDI/BPDRF RCT）是一项针对边缘型人格障碍（BPD）的对照结局研究，90名参与者被随机分配到三种手册化且受监测的积极社会心理治疗条件之一。这些治疗方法分别是：（a）移情焦点心理治疗（TFP；克拉金、约曼斯和克恩伯格，1999年），一种基于客体关系和精神分析原则的BPD治疗方法，最初由克恩伯格（1996年）应用于BPD，其特别强调对正在进行的治疗关系中激活的客体关系进行解释；（b）辩证行为疗法（DBT；莱因汉，1993年），一种广受欢迎的BPD治疗方法，有疗效证据（莱因汉、阿姆斯特朗、苏亚雷斯、奥尔蒙和赫德，1991年），该方法在认知行为和禅宗原则的结合中强调接纳与改变之间的平衡；（c）支持性心理治疗（罗克兰，1992年），另一种基于客体关系和精神分析的BPD治疗方法，与TFP不同的是，它避免移情解释，主要强调与患者建立合作关系以促进身份认同发展。如果有明确指征，患者会根据索洛夫（2000年）制定的治疗算法接受药物治疗。本文描述了该研究的意义、原理、总体设计、方法、分析计划以及所招募患者样本的人口统计学特征。
