van den Brandhof W E, De Wit G A, de Wit M A S, van Duynhoven Y T H P
Department of Infectious Diseases Epidemiology, National Institute of Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
Epidemiol Infect. 2004 Apr;132(2):211-21. doi: 10.1017/s0950268803001559.
In order to target the most important cost components of gastroenteritis in The Netherlands and to indicate which change of policy yields the largest decrease in costs, the cost of illness of gastroenteritis and the number of Disability Adjusted Life Years (DALYs) in the Dutch population in 1999 were determined. The costs of gastroenteritis were estimated using data mainly from a community-based cohort study. For calculating DALYs, data on the number of deaths due to gastroenteritis were used from Statistics Netherlands. On average, the costs for gastroenteritis were 77 Euro (euros) per case. For all patients in The Netherlands, the costs were estimated at 345 million euros (ranging between 252 and 531 million euros). Indirect costs made up 82% of this total. An estimate of costs for patients with campylobacter, salmonella or norovirus infections was, in total, 10-17% of the costs of gastroenteritis. Gastroenteritis was associated with a loss of approximately 67,000 DALYs.
为了确定荷兰肠胃炎最重要的成本构成部分,并指出哪种政策变化能使成本降幅最大,我们确定了1999年荷兰人群肠胃炎的疾病成本和伤残调整生命年(DALY)数量。肠胃炎的成本主要根据一项基于社区的队列研究数据进行估算。计算DALY时,使用了荷兰统计局提供的肠胃炎死亡人数数据。肠胃炎平均每例成本为77欧元。对于荷兰所有患者,成本估计为3.45亿欧元(介于2.52亿至5.31亿欧元之间)。间接成本占总成本的82%。弯曲杆菌、沙门氏菌或诺如病毒感染患者的成本估计总计占肠胃炎成本的10%-17%。肠胃炎导致约67000个DALY的损失。