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吞噬细胞:炎症与组织破坏机制

Phagocytes: mechanisms of inflammation and tissue destruction.

作者信息

Liu Hongtao, Pope Richard M

机构信息

Division of Rheumatology, Department of Medicine, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Ward 3-315, Chicago, IL 60611, USA.

出版信息

Rheum Dis Clin North Am. 2004 Feb;30(1):19-39, v. doi: 10.1016/S0889-857X(03)00107-8.

DOI:10.1016/S0889-857X(03)00107-8
PMID:15061567
Abstract

Macrophages and neutrophils are the professional phagocytes of the innate immune system. Once in the inflammatory joint or the vasculitic lesion, macrophages and neutrophils contribute to the pathology observed. This article examines the mechanisms by which phagocytes contribute to the pathogenesis of these diseases.

摘要

巨噬细胞和中性粒细胞是先天性免疫系统中的专职吞噬细胞。一旦进入炎症关节或血管炎病变部位,巨噬细胞和中性粒细胞就会促使出现所观察到的病理变化。本文探讨了吞噬细胞促使这些疾病发病的机制。

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