Lembo Anthony J
Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Hospital, Dana 501, 330 Brookline Avenue, Boston, MA 02215, USA.
Gastroenterol Clin North Am. 2004 Mar;33(1):55-60. doi: 10.1016/S0889-8553(03)00134-1.
Visceral hypersensitivity is a common cause of NCCP. Mechanoreceptors appear to be important in the pathophysiology of NCCP, although chemoreceptors also appear to play a significant role. The processing of visceral information and possibly the development of central sensitization may be important in NCCP, although the pathophysiology of NCCPremains poorly understood.