Giamberardino M A, Vecchiet L
Pathophysiology of Pain Laboratory, G. D'Annuznio University of Chieti, Italy.
Eur J Anaesthesiol Suppl. 1995 May;10:61-6.
Visceral pain is a poorly defined, midline sensation but after minutes or hours becomes 'referred' to a somatic region when it becomes sharper and better localized. Referred pain may manifest either with or without hyperalgesia. Hyperalgesia is more common and can be demonstrated by changes in pain threshold. This referred hyperalgesia is probably sustained by central mechanisms, involving a spinal focus facilitating neuronal signals coming from somatic structures. Once established, the central changes may become independent of the peripheral input necessary for their initiation. With respect to post-surgical pain associated with operations on the viscus, the main determinant is whether or not the visceral pathology prior to surgery was algogenic.
内脏痛是一种定义不明确的中线感觉，但在数分钟或数小时后，当疼痛变得更剧烈且定位更准确时，会“牵涉”到躯体部位。牵涉痛可能伴有或不伴有痛觉过敏。痛觉过敏更为常见，可通过痛阈变化来证实。这种牵涉性痛觉过敏可能由中枢机制维持，涉及脊髓部位促进来自躯体结构的神经元信号。一旦确立，中枢变化可能变得独立于其起始所需的外周输入。对于与内脏手术相关的术后疼痛，主要决定因素是术前内脏病理是否会引发疼痛。
