Ramey Sandra L, Franke Warren D, Shelley Mack C
Marquette University, College of Nursing, Milwaukee, WI, USA.
AAOHN J. 2004 Mar;52(3):116-21.
This cross-sectional study determined the prevalence of nephrolithiasis and common cardiovascular disease (CVD) risk factors in a law enforcement officer (LEO) cohort and evaluated the relationship of nephrolithiasis with several CVD risk factors, including the possible effect of ethnicity. Self reported nephrolithiasis and CVD risk factors among currently employed male LEOs from nine states (n = 2,818) were compared to other men in the same states (n = 9,650). Of the LEOs, 6.2% (n = 174) self reported at least one kidney stone (range = 1 to 12, mean 2.3 6 2.1 stones). Twenty five percent of Native American LEOs (n = 7 of 28) self reported a history of stones. In LEOs with a history of nephrolithiasis, overweight defined as body mass index . 25 kg/m2 (odds ratio [OR] = 1.80, 95% confidence interval [CI] = 1.04, 3.11), hypercholesterolemia (OR = 1.53, 95% CI = 1.09, 2.15), and hypertension (OR = 1.46, 95% CI = 1.02, 2.11) were associated with the disease. These results suggest officers with common CVD risk factors are also at an increased risk for nephrolithiasis. Native American LEOs have a disproportionately higher prevalence of nephrolithiasis than do other ethnic groups.
这项横断面研究确定了执法人员队列中肾结石和常见心血管疾病（CVD）危险因素的患病率，并评估了肾结石与几种CVD危险因素之间的关系，包括种族的可能影响。将来自九个州的在职男性执法人员（n = 2,818）自我报告的肾结石和CVD危险因素与同一州的其他男性（n = 9,650）进行比较。在执法人员中，6.2%（n = 174）自我报告至少有一颗肾结石（范围 = 1至12颗，平均2.3 ± 2.1颗结石）。25%的美国原住民执法人员（n = 28人中的7人）自我报告有结石病史。在有肾结石病史的执法人员中，体重指数>25 kg/m²定义的超重（优势比[OR] = 1.80，95%置信区间[CI] = 1.04，3.11）、高胆固醇血症（OR = 1.53，95% CI = 1.09，2.15）和高血压（OR = 1.46，95% CI = 1.02，2.11）与该疾病相关。这些结果表明，具有常见CVD危险因素的警察患肾结石的风险也增加。美国原住民执法人员肾结石的患病率比其他种族群体高得多。
