通过同种异体刺激激活猪巨细胞病毒。
Reactivation of porcine cytomegalovirus through allogeneic stimulation.
作者信息
Guedes Maria Isabel M C, Risdahl Jack M, Wiseman Barry, Molitor Thomas W
机构信息
Department of Clinical and Population Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108, USA.
出版信息
J Clin Microbiol. 2004 Apr;42(4):1756-8. doi: 10.1128/JCM.42.4.1756-1758.2004.
Abstract
Reactivation of latent porcine cytomegalovirus after coculture of peripheral blood mononuclear cells (PBMCs) from pigs with different genetic backgrounds was investigated. Nine of 10 allogeneic coculture pairs were PCR (DNA) positive, whereas 7 coculture pairs had porcine cytomegalovirus (PCMV) RNA, an indication of virus replication. The cell subpopulations harboring PCMV were monocytes and CD8+ T cells.
摘要
研究了来自不同遗传背景猪的外周血单个核细胞（PBMCs）共培养后潜伏性猪巨细胞病毒的重新激活情况。10对异基因共培养物中有9对PCR（DNA）呈阳性，而7对共培养物有猪巨细胞病毒（PCMV）RNA，这表明病毒在复制。携带PCMV的细胞亚群是单核细胞和CD8 + T细胞。
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1
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2
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Vet Immunol Immunopathol. 2001 Jul 20;80(1-2):5-23. doi: 10.1016/s0165-2427(01)00290-2.
3
Isolation and purification of lymphocyte subsets from gut-associated lymphoid tissue in neonatal swine.新生猪肠道相关淋巴组织中淋巴细胞亚群的分离与纯化。
J Immunol Methods. 2000 Jul 31;241(1-2):185-99. doi: 10.1016/s0022-1759(00)00209-x.
4
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5
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Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3937-42. doi: 10.1073/pnas.95.7.3937.
6
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7
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Intervirology. 1996;39(5-6):293-301. doi: 10.1159/000150501.
8
The relationship between T-cell levels and CMV infection in asymptomatic HIV-1 antibody-positive homosexual men.无症状HIV-1抗体阳性同性恋男性中T细胞水平与巨细胞病毒感染的关系。
J Acquir Immune Defic Syndr (1988). 1993 Apr;6(4):407-13.
9
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J Infect Dis. 1995 Aug;172(2):365-70. doi: 10.1093/infdis/172.2.365.
10
Primary cytomegalovirus infection in pregnancy. Incidence, transmission to fetus, and clinical outcome.妊娠期原发性巨细胞病毒感染。发病率、胎儿传播及临床结局。
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