Rhodes Tim, Judd Ali, Mikhailova Larissa, Sarang Anya, Khutorskoy Mikhail, Platt Lucy, Lowndes Catherine M, Renton Adrian
The Centre for Research on Drugs and Health Behaviour and Department for International Development Knowledge Programme in HIV/AIDS, Imperial College Faculty of Medicine, University of London, United Kingdom.
J Acquir Immune Defic Syndr. 2004 Mar 1;35(3):293-300. doi: 10.1097/00126334-200403010-00011.
To compare risk factors for injecting equipment sharing among injecting drug users (IDUs) in Togliatti City, Russia.
Unlinked, anonymous, cross-sectional community-recruited survey with oral fluid sample collection.
Between September and October 2001, 426 IDUs completed an interviewer-administered questionnaire and oral fluid samples were tested for HIV. Univariate and multivariate analyses compared potential risk factors for injecting equipment sharing.
More than half (56% [234/418]) of the sample were positive for antibodies to HIV. A third (36%) had injected with used needles and syringes in the last 4 weeks. IDUs who reported syringe exchanges or outreach workers as their main sources of new needles and syringes in the last 4 weeks had 0.3 times the odds of sharing compared with those obtaining them from a pharmacy or shop, whereas those whose main source was buying them from the streets or obtaining them from friends, sexual partners, or other drug users had 12 times the odds of receptive needle and syringe sharing. IDUs who reported being last arrested or detained by the police for a drug-related offense had higher odds of sharing.
Findings highlight the delicate balance in HIV prevention between potentially competing strategies of law enforcement and syringe distribution.
比较俄罗斯陶里亚蒂市注射吸毒者(IDU)之间共用注射器具的风险因素。
通过社区招募进行无关联、匿名的横断面调查,并采集口腔液样本。
2001年9月至10月期间,426名注射吸毒者完成了由访谈员填写的问卷,并对口腔液样本进行了HIV检测。单因素和多因素分析比较了共用注射器具的潜在风险因素。
超过一半(56%[234/418])的样本HIV抗体呈阳性。三分之一(36%)的人在过去4周内使用过用过的针头和注射器。在过去4周内报告通过注射器交换或外展工作人员获得新针头和注射器的注射吸毒者,其共用的几率是从药店或商店获得这些器具者的0.3倍,而那些主要从街头购买或从朋友、性伴侣或其他吸毒者处获得针头和注射器的人,接受共用针头和注射器的几率则是前者的12倍。报告最近因毒品相关罪行被警方逮捕或拘留的注射吸毒者共用的几率更高。
研究结果凸显了在艾滋病毒预防方面,执法和注射器分发这两种潜在相互竞争的策略之间的微妙平衡。