Figueiro Mariana G, Bullough John D, Parsons Robert H, Rea Mark S
Lighting Research Center, Rensselaer Polytechnic Institute, 21 Union Street, Troy, NY 12180, USA.
Neuroreport. 2004 Feb 9;15(2):313-6. doi: 10.1097/00001756-200402090-00020.
Human adult males were exposed to light from blue light emitting diodes (18 lux; 29 microW/cm) and from clear mercury vapor lamps (450 lux; 170 microW/cm) during night-time experimental sessions. Both conditions suppressed nocturnal melatonin concentrations in blood plasma with the blue light more effective than mercury at melatonin suppression. No additive model incorporating opsin photopigments either alone or in combination could explain the results, but a model incorporating an opponent mechanism was consistent with the present data as well as data from previously published studies.
在夜间实验期间，成年男性被暴露于蓝光发光二极管发出的光（18勒克斯；29微瓦/平方厘米）和透明汞蒸气灯发出的光（450勒克斯；170微瓦/平方厘米）下。两种条件都抑制了血浆中夜间褪黑激素的浓度，其中蓝光在抑制褪黑激素方面比汞更有效。单独或组合纳入视蛋白光色素的任何加性模型都无法解释这些结果，但纳入对抗机制的模型与当前数据以及先前发表研究的数据一致。
