So Tetsuya, Osaki Toshihiro, Nakata Shoji, Hanagiri Takeshi, Sugio Kenji, Yasumoto Kosei
Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Jpn J Thorac Cardiovasc Surg. 2004 Mar;52(3):143-7. doi: 10.1007/s11748-004-0131-y.
We herein describe 3 cases of a carinal resection after induction bronchial arterial infusion (BAI) for locally advanced non-small cell lung cancer (NSCLC). Case 1 was a 44-year-old man with T1N2M0 adenocarcinoma. After undergoing Nd-YAG laser treatment (5079 J) and BAI [cis-diamminedichloro platinum (CDDP) 100 mg/body], a right sleeve upper lobectomy with a carinal resection and reconstruction (Montage type) was performed. Case 2 was a 67-year-old man with T4N1M0 squamous cell carcinoma. After BAI (CDDP 120 mg/body), an operation (same as case 1) was performed. Case 3 was a 72-year-old man with T4N2M0 squamous cell carcinoma. After BAI (CDDP 120 mg/body), a right sleeve peumonectomy was performed. There was neither BAI-related intraoperative nor postoperative complications. BAI with CDDP was thus found to be a useful and effective therapeutic modality for locally advanced NSCLC invading the carina.
我们在此描述3例局部晚期非小细胞肺癌(NSCLC)经诱导支气管动脉灌注(BAI)后行隆突切除术的病例。病例1为一名44岁男性,患有T1N2M0腺癌。在接受Nd-YAG激光治疗(5079焦耳)和BAI[顺二氯二氨铂(CDDP)100毫克/体]后,进行了右袖式上叶切除术并隆突切除重建(蒙太奇式)。病例2为一名67岁男性,患有T4N1M0鳞状细胞癌。在接受BAI(CDDP 120毫克/体)后,进行了手术(与病例1相同)。病例3为一名72岁男性,患有T4N2M0鳞状细胞癌。在接受BAI(CDDP 120毫克/体)后,进行了右袖式全肺切除术。未发现与BAI相关的术中及术后并发症。因此,发现CDDP联合BAI是治疗侵犯隆突的局部晚期NSCLC的一种有用且有效的治疗方式。