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英国过敏性疾病负担:国家数据库的二次分析

Burden of allergic disease in the UK: secondary analyses of national databases.

作者信息

Gupta R, Sheikh A, Strachan D P, Anderson H R

机构信息

Department of Community Health Sciences, St George's Hospital Medical School, London, UK.

出版信息

Clin Exp Allergy. 2004 Apr;34(4):520-6. doi: 10.1111/j.1365-2222.2004.1935.x.

Abstract

BACKGROUND

Although allergy represents an important source of patient morbidity and healthcare utilization, there is little reliable information on the overall disease burden posed by allergic conditions in the UK.

OBJECTIVES

Focusing on the following conditions: allergic rhinitis, anaphylaxis, asthma, conjunctivitis, eczema/dermatitis, food allergy and urticaria/angioedema, we sought to (i) describe the prevalence, incidence and outcomes of allergic disorders; (ii) describe the NHS healthcare burden posed by allergic disorders; (iii) estimate the costs of allergic disorders from a healthcare perspective.

METHODS

Secondary analyses of data from the Health Survey for England, Scottish Health Survey, International Study of Allergies and Asthma in Childhood, European Community Respiratory Health Survey, Morbidity Statistics from General Practice 1991/1992, Royal College of General Practitioners Weekly Returns Service, Prescribing Analysis and Cost data, Hospital Episodes Statistics and national mortality data.

RESULTS

Thirty-nine percent of children and 30% of adults have been diagnosed with one or more atopic conditions. Six percent of general practice consultations and 0.8% of hospital admissions are for allergic diseases. Treatments for asthma and other allergic disorders currently account for 10% of primary care prescribing costs. Direct NHS costs for managing allergic problems are estimated at over one billion UK pounds per annum.

CONCLUSIONS

Allergic disorders are common throughout the UK, affecting males and females of all ages and peoples from all social classes and ethnic groups. They currently represent a substantial burden of morbidity and health service cost.

摘要

背景

尽管过敏是患者发病和医疗资源利用的一个重要来源,但关于英国过敏性疾病所造成的总体疾病负担,几乎没有可靠信息。

目的

聚焦于以下疾病:过敏性鼻炎、过敏反应、哮喘、结膜炎、湿疹/皮炎、食物过敏以及荨麻疹/血管性水肿,我们试图:(i)描述过敏性疾病的患病率、发病率及转归;(ii)描述过敏性疾病给英国国民医疗服务体系(NHS)带来的医疗负担;(iii)从医疗保健角度估算过敏性疾病的成本。

方法

对来自英格兰健康调查、苏格兰健康调查、儿童变应性疾病和哮喘国际研究、欧洲共同体呼吸健康调查、1991/1992年全科医疗发病率统计、皇家全科医师学院每周回报服务、处方分析与成本数据、医院事件统计以及国家死亡率数据进行二次分析。

结果

39%的儿童和30%的成年人被诊断患有一种或多种特应性疾病。6%的全科医疗咨询和0.8%的住院是因过敏性疾病。目前,哮喘和其他过敏性疾病的治疗费用占初级保健处方成本的10%。英国国民医疗服务体系管理过敏性问题的直接成本估计每年超过10亿英镑。

结论

过敏性疾病在英国普遍存在,影响所有年龄、所有社会阶层和种族群体的男性和女性。目前,它们构成了相当大的发病负担和卫生服务成本。

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