Barmettler Hanna, Immer Franz F, Berdat Pascal A, Eckstein Friedrich S, Kipfer Beat, Carrel Thierry P
Department of Cardiovascular Surgery, University Hospital,CH-3010 Berne, Switzerland.
Eur J Cardiothorac Surg. 2004 May;25(5):691-4. doi: 10.1016/j.ejcts.2004.01.003.
Risk-stratification in cardiac surgical procedures is of major interest. Recent studies have shown, that the EuroSCORE is a very good and reliable risk-stratification score in CABG and in valve surgery. The aim of the study was to evaluate the EuroSCORE in patients undergoing surgery on the thoracic aorta.
Three hundred and sixty-seven consecutive patients underwent surgery of the thoracic aorta and were scored, according to the additive and logistic EuroSCORE algorithm. We compared correlation of predicted and observed mortality and evaluated a modification of the EuroSCORE in order to improve the scoring system. Score validity was assessed by calculating the area under the receiver operating characteristic curve (ROC).
Overall hospital mortality was 10.1%. Additive EuroSCORE predicted mortality was 2.3% for 3-6% risk, 12.9% for 7-8% risk, 18.4% for 9-12% risk and 27.3% for a risk >12%. The modified score predicted mortality was 1% for 3-6% risk, 8.2% for 7-8% risk, 12.1% for 9-14% risk, 18.6% for 15-24% risk and 28.6% for a risk >24%. Area under the ROC-curve was 0.68 for the EuroScore and 0.91 in the modified score, 0.72 and 0.86 in the logistic model.
The modified score, taking into account aortic dissection (6 points) and preoperative malperfusion (12 points) significantly improves the predictive value of the EuroSCORE in patients undergoing thoracic aortic surgery.
心脏外科手术中的风险分层备受关注。近期研究表明,欧洲心脏手术风险评估系统(EuroSCORE)在冠状动脉旁路移植术(CABG)和瓣膜手术中是一个非常好且可靠的风险分层评分系统。本研究的目的是评估EuroSCORE在胸主动脉手术患者中的应用。
367例连续接受胸主动脉手术的患者,根据EuroSCORE的相加法和逻辑回归法进行评分。我们比较了预测死亡率与观察到的死亡率之间的相关性,并评估了EuroSCORE的一种改进方法,以完善评分系统。通过计算受试者工作特征曲线(ROC)下的面积来评估评分的有效性。
总体医院死亡率为10.1%。相加法EuroSCORE预测的死亡率在3 - 6%风险时为2.3%,7 - 8%风险时为12.9%,9 - 12%风险时为18.4%,风险>12%时为27.3%。改进后的评分预测的死亡率在3 - 6%风险时为1%,7 - 8%风险时为8.2%,9 - 14%风险时为12.1%,15 - 24%风险时为18.6%,风险>24%时为28.6%。EuroSCORE的ROC曲线下面积为0.68,改进后的评分为0.91,逻辑回归模型分别为0.72和0.86。
改进后的评分系统,考虑了主动脉夹层(6分)和术前灌注不良(12分),显著提高了EuroSCORE在胸主动脉手术患者中的预测价值。