Suppr超能文献

胸主动脉手术中的风险分层:欧洲心脏手术风险评估系统(EuroSCORE)是否应进行修改?

Risk-stratification in thoracic aortic surgery: should the EuroSCORE be modified?

作者信息

Barmettler Hanna, Immer Franz F, Berdat Pascal A, Eckstein Friedrich S, Kipfer Beat, Carrel Thierry P

机构信息

Department of Cardiovascular Surgery, University Hospital,CH-3010 Berne, Switzerland.

出版信息

Eur J Cardiothorac Surg. 2004 May;25(5):691-4. doi: 10.1016/j.ejcts.2004.01.003.

Abstract

OBJECTIVES

Risk-stratification in cardiac surgical procedures is of major interest. Recent studies have shown, that the EuroSCORE is a very good and reliable risk-stratification score in CABG and in valve surgery. The aim of the study was to evaluate the EuroSCORE in patients undergoing surgery on the thoracic aorta.

METHODS

Three hundred and sixty-seven consecutive patients underwent surgery of the thoracic aorta and were scored, according to the additive and logistic EuroSCORE algorithm. We compared correlation of predicted and observed mortality and evaluated a modification of the EuroSCORE in order to improve the scoring system. Score validity was assessed by calculating the area under the receiver operating characteristic curve (ROC).

RESULTS

Overall hospital mortality was 10.1%. Additive EuroSCORE predicted mortality was 2.3% for 3-6% risk, 12.9% for 7-8% risk, 18.4% for 9-12% risk and 27.3% for a risk >12%. The modified score predicted mortality was 1% for 3-6% risk, 8.2% for 7-8% risk, 12.1% for 9-14% risk, 18.6% for 15-24% risk and 28.6% for a risk >24%. Area under the ROC-curve was 0.68 for the EuroScore and 0.91 in the modified score, 0.72 and 0.86 in the logistic model.

CONCLUSIONS

The modified score, taking into account aortic dissection (6 points) and preoperative malperfusion (12 points) significantly improves the predictive value of the EuroSCORE in patients undergoing thoracic aortic surgery.

摘要

目的

心脏外科手术中的风险分层备受关注。近期研究表明,欧洲心脏手术风险评估系统(EuroSCORE)在冠状动脉旁路移植术(CABG)和瓣膜手术中是一个非常好且可靠的风险分层评分系统。本研究的目的是评估EuroSCORE在胸主动脉手术患者中的应用。

方法

367例连续接受胸主动脉手术的患者,根据EuroSCORE的相加法和逻辑回归法进行评分。我们比较了预测死亡率与观察到的死亡率之间的相关性,并评估了EuroSCORE的一种改进方法,以完善评分系统。通过计算受试者工作特征曲线(ROC)下的面积来评估评分的有效性。

结果

总体医院死亡率为10.1%。相加法EuroSCORE预测的死亡率在3 - 6%风险时为2.3%,7 - 8%风险时为12.9%,9 - 12%风险时为18.4%,风险>12%时为27.3%。改进后的评分预测的死亡率在3 - 6%风险时为1%,7 - 8%风险时为8.2%,9 - 14%风险时为12.1%,15 - 24%风险时为18.6%,风险>24%时为28.6%。EuroSCORE的ROC曲线下面积为0.68,改进后的评分为0.91,逻辑回归模型分别为0.72和0.86。

结论

改进后的评分系统,考虑了主动脉夹层(6分)和术前灌注不良(12分),显著提高了EuroSCORE在胸主动脉手术患者中的预测价值。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验