Matsumoto Kenji, Tanaka Keiji
Cognitive Brain Mapping Laboratory, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan.
Curr Opin Neurobiol. 2004 Apr;14(2):178-85. doi: 10.1016/j.conb.2004.03.005.
Achieving goals in changing environments requires the course of action to be selected on the basis of goal expectation and memory of action-outcome contingency. It is often also essential to evaluate action on the basis of immediate outcomes and the discrimination of early action steps from the final step towards the goal. Recently, in single-cell recordings in monkeys, the neuronal activity that appears to underlie these processes has been noted in the medial part of the prefrontal cortex. Medial prefrontal cells were also active when the subjects extracted the rules of a task in a novel environment. The processes described above might play important roles in rule learning.
在不断变化的环境中实现目标需要根据目标期望和行动-结果偶然性的记忆来选择行动过程。根据即时结果以及区分朝着目标的早期行动步骤和最终步骤来评估行动通常也很重要。最近，在对猴子的单细胞记录中，前额叶皮层内侧部分出现了似乎是这些过程基础的神经元活动。当受试者在新环境中提取任务规则时，内侧前额叶细胞也会活跃。上述过程可能在规则学习中发挥重要作用。
