Liu J, Liang P, Yin C, Wang T, Li H, Li Y, Ye Z
Department of Urology, Tongji Hospital, Wuhan, China.
Andrologia. 2004 Apr;36(2):78-83. doi: 10.1111/j.1439-0272.2004.00607.x.
The effects of six kinds of aqueous extracts of Chinese herbal medicine (Astragalus membranaceus, Acanthopanacis senticosi, Panax genseng and Ophiopogon japonicus, P. genseng and Aconitum carmichaeli, Salviae miltiorrhiae, Polyporus umbellatus polysaccharide) on sperm motility characteristics of 30 infertile male volunteers were studied in vitro with a computer-assisted sperm analysis at 15, 60 and 180 min after incubated with the drugs. The results showed that per cent viability, number of progressive motile spermatozoa, curvilinear velocity, average path velocity and amplitude of lateral head displacement were significantly enhanced by A. membranaceus (P < 0.05 or < 0.01), per cent viability, average path velocity and amplitude of lateral head displacement were significantly enhanced by A. senticosi (P < 0.05), but all the above were not affected by P. genseng and O. japonicus, P. genseng and A. carmichaeli, S. miltiorrhiae and P. umbellatus polysaccharide. It is suggested that A. membranaceus and A. senticosi can enhance the motility of human spermatozoa in vitro.
采用计算机辅助精子分析技术，在体外研究了六种中药水提取物（黄芪、刺五加、人参和麦冬、人参和附子、丹参、猪苓多糖）作用于30名男性不育志愿者精子15、60和180分钟后对精子运动特性的影响。结果显示，黄芪能显著提高精子活率、前向运动精子数、曲线速度、平均路径速度和侧摆幅值（P<0.05或<0.01），刺五加能显著提高精子活率、平均路径速度和侧摆幅值（P<0.05），而人参和麦冬、人参和附子、丹参及猪苓多糖对上述指标均无影响。提示黄芪和刺五加在体外可提高人精子的运动能力。
