Khaleghi Sara, Bakhtiari Mitra, Asadmobini Atefeh, Esmaeili Farzane
1 Medical Biology Research Center, Kermanshah University of medical sciences, Kermanshah, Iran.
2 Fertility & Infertility Research Center, Kermanshah University of Medical Sciences, Sorkheh Lizheh, Kermanshah, Iran.
J Evid Based Complementary Altern Med. 2017 Jul;22(3):407-412. doi: 10.1177/2156587216668110. Epub 2016 Sep 30.
The object of present study was to investigate the effects of direct addition of Tribulus terrestris extract on human sperm parameters.
Semen specimens from 40 healthy men volunteers were divided into 4 groups: one group received no treatment (control group) while the others were incubated with 20, 40, and 50 µg/mL of T terrestris extract (experimental groups). Motility, viability, and DNA fragmentation were assessed in all groups.
The incubation of human semen with 40 and 50 μg/mL of T terrestris extract significantly enhanced total sperm motility, number of progressive motile spermatozoa, and curvilinear velocity over 60 to 120 minutes' holding time ( P < .05 or P < < .01). Furthermore, viability was significantly enhanced by using T terrestris extract ( P < .01).
In vitro addition of the T terrestris extract to human sperm could affect male fertility capacity.
本研究旨在探讨直接添加刺蒺藜提取物对人类精子参数的影响。
将40名健康男性志愿者的精液标本分为4组：一组不接受治疗（对照组），其他组分别与20、40和50μg/mL的刺蒺藜提取物一起孵育（实验组）。评估所有组的精子活力、存活率和DNA片段化情况。
在60至120分钟的保存时间内，用40和50μg/mL的刺蒺藜提取物孵育人精液显著提高了总精子活力、进行性运动精子数量和曲线速度（P<.05或P<<.01）。此外，使用刺蒺藜提取物显著提高了精子存活率（P<.01）。
体外向人类精子中添加刺蒺藜提取物可能会影响男性生育能力。
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