Timmons Suzanne, Liston Richard, Moriarty Kieran J
South Munster Specialist Registrar Training Scheme, Tralee General Hospital, Co. Kerry, Ireland.
Am J Gastroenterol. 2004 Apr;99(4):739-49. doi: 10.1111/j.1572-0241.2004.04086.x.
Functional dyspepsia is a common condition, but as yet, the underlying etiology is unclear. In this article, upper gastrointestinal motor and sensory physiology are reviewed and the current evidence for motor and/or sensory functional abnormalities causing dyspeptic symptoms is presented. The complex interrelationship between abnormal motor activity and sensation is explored, as well as the potential roles for autonomic dysfunction and psychological state in modulating gastrointestinal sensation and motor function. Finally, based on clinical trial evidence, a treatment pathway for functional dyspepsia is suggested.
功能性消化不良是一种常见病症，但目前其潜在病因尚不清楚。本文回顾了上消化道运动和感觉生理学，并阐述了导致消化不良症状的运动和/或感觉功能异常的现有证据。探讨了异常运动活动与感觉之间的复杂相互关系，以及自主神经功能障碍和心理状态在调节胃肠感觉和运动功能中的潜在作用。最后，基于临床试验证据，提出了功能性消化不良的治疗途径。
